Chronic and even acute inflammation may be responsible for dementia. A look at the research certainly points towards a connection.
"Healthy older adults randomized to speed of processing cognitive training had a 29% reduction in their risk of dementia after 10 years of follow-up compared to the untreated control group."
Older adults with mild cognitive impairment (MCI) who engaged in moderate physical activity had greater hippocampal volume. Atrophy of the hippocampus is a hallmark of Alzheimer's, therefore these results suggest that exercise can help to stave off Alzheimer's.
Individuals at higher risk for Alzheimer's who engaged in little to no physical activity lost 3% of their hippocampal volume after only 18 months. Those who did moderate physical activity showed no change in the volume of the hippocampus.
Alzheimer's subjects given probiotics showed improvement in some (but not all) measures of Alzheimer's pathology. Importantly, the probiotics did improve cognitive function.
A study of probiotic supplementation clearly showed that the probiotic formula protected Alzheimer's mice from neurodegeneration as measured by cognitive function and signs of brain damage.
This 2017 study from the University of Wisconsin compared the microbiota of 25 people diagnosed with Alzheimer's and 25 age and sex-matched control participants. The Alzheimer's group showed decreased levels of "good" bacteria and increased levels of "bad" bacteria.
Mice bred to develop Alzheimer's-like symptoms were given a drug that increased sensitivity to hormones shown to combat diabetes. The mice showed memory improvement to near normal levels.
Simple Summary Metabolic syndrome, and type 2 diabetes (T2D) are related disorders that damage (among other things) the brain. Both conditions contribute to impaired cognitive function, and increase the risk of Alzheimer's. More Detail Metabolic syndrome is characterized by belly fat, elevated cholesterol, elevated blood pressure, insulin resistance, increased risk of blood clots and inflammation. Metabolic syndrome, if uncorrected, eventually damages the pancreas leading to a decrease of insulin secretion. "The fall in insulin secretion leading to hyperglicemia occurs as a late phenomenon and, in fact, separates the patients with metabolic syndrome from those with or without overt diabetes."(R) Persons with metabolic disorders are at significantly increased risk for cognitive decline and the development of vascular dementia and Alzheimer’s disease. Those with T2D are at even greater risk. Into The Weeds Insulin Resistance: Insulin is a peptide hormone produced by the Beta cells in the pancreas which also serve as glucose level monitors. As the beta cells in the pancreas detect increasing levels of glucose (a simple sugar) they step up insulin production. When someone is insulin resistance, their cells are unable to take up glucose, and the result is hyperglycemia (an increase in [...]
It looks like your mother had it all wrong. Playing video games does not destroy your brain, in fact it can make your brain bigger and help to avoid Alzheimer's.
UCLA reversed dementia in 9 human subjects using a combination of exercise, diet, brain games, and a dietary supplement.
An FDA approved drug reduces energy requirements in neurons. Relieved from the pressure of protein production the mitochondria can produce energy for cellular repair processes.